NuGenTec's BioTech Product Line has been carefully selected and sourced to provide the highest quality and purity. Our select line of BioTech / Pharma Chemicals meets the most stringent standards current to the industry. Our Class 100 CleanRoom blending and filling area is specifically designed with the needs of the BioTech and Semiconductor Industries in mind. Nugentec is unique in the range of products available and offers a level of customer service that sets us apart from the competition. With the ideal of constant improvement and the needs of our customers, we believe NuGenTec can and will prove to be a leader in the industry. We are committed and dedicated to serve you to the very best of our ability. We look forward to establishing and maintaining the quality relationship which you deserve.

CORE PRODUCTS:

• Acetone
• Acetonitrile
• DMF (Dimethylformamide)
  • DMF is a solvent with a low evaporation rate. Used as a solvent in peptide coupling for pharmaceuticals.
  • Fmoc solid-phase peptide synthesis: To remove an Fmoc from a growing peptide chain, basic conditions (usually 20% piperidine in DMF) are used.
  • Alloc protecting group: used to wash off resin.
  • Protected amino acids dissolved in a solvent such as dimethylformamide (DMF)
• IPA (Isopropyl Alcohol)
• Methanol (methyl alcohol)
• Methylene Chloride (DCM)
• NMP (N-Methyl-2-pyrrolidone, N-Methyl Pyrrolidone): is the lactam of 4-methylaminobutyric acid and a very weak base. NMP is a chemically stable and powerful polar solvent. These characteristics are highly useful in a variety of chemical reactions where an inert medium is of concern. Despite the stability of NMP, it can also play an active role in certain reactions: hydrolysis, oxidation, condensation, conversion with chlorinating agents, polymerization and o-alkylation, and related reactions
  • PEG based Resins
• Piperidine
  • Fmoc solid-phase peptide synthesis: To remove an Fmoc from a growing peptide chain, basic conditions (usually 20% piperidine in DMF) are used.
  • ***(Listed on US Controlled Substances Act)***
    • Purchasing Requirements
      1. DEA Licence Mandatory for Purchase
      2. NuGenTec BioTech Sales must approve your company before an order may be placed.
         1. On-Site Inspection Required.
         2. All DEA forms on File.
         3. NO COD or CASH or Will Call orders.
• TFA (Trifluoroacetic acid)
  • t-Boc solid-phase peptide synthesis
  • Fmoc solid-phase peptide synthesis
  • PEG based Resin

Products listed above supplied in bulk, 55-gallon drums, 5-gallon pails and 4x1-gallon cases.

A great short course video Biochemistry: The Amino Acids, Peptides, and Proteins. Courtesy of MIT / CHEMISTRY

By Donald R. Sadoway

COURSE DESCRIPTION

This course explores the basic principles of chemistry and their application to engineering systems. It deals with the relationship between electronic structure, chemical bonding, and atomic order. It also investigates the characterization of atomic arrangements in crystalline and amorphous solids: metals, ceramics, semiconductors, and polymers (including proteins). Topics covered include organic chemistry, solution chemistry, acid-base equilibria, electrochemistry, biochemistry, chemical kinetics, diffusion, and phase diagrams. Examples are drawn from industrial practice (including the environmental impact of chemical processes), from energy generation and storage, e.g., batteries and fuel cells, and from emerging technologies, e.g., photonic and biomedical devices. 

BIOPROCESSING Biomaterials news

Scientific American - Biotechnology

Researchers Gain New Insights into the Mystery of Thalidomide-Caused Birth Defects Half a century ago, thousands of pregnant women in 46 countries took a drug for morning sickness that would later be discovered to cause severe malformations in developing fetuses. Worldwide, roughly 10,000 affected children nicknamed "thalidomide babies" were born with multiple defects, including the characteristic shortened upper limbs (a condition known as phocomelia, Greek for "seal limbs"), before the drug was discontinued in 1961 after four years on the market. [More]

New Hope for Battling Brain Cancer (preview) In May 2006 Dwayne Berg woke up on a gurney in a Seattle emergency room, an IV in his arm and a team of doctors and nurses working him up. The last thing the 42-year-old financial executive could remember was running on a treadmill at his gym, part of his regular fitness regimen. He had suffered a seizure and tumbled off the machine, and although he had not hurt himself in the fall, doctors had asked for an MRI scan of his brain to see if they could find a cause for the seizure. They did, and the news was not good: the scan showed a large mass in the left frontal lobe that turned out to be a malignant glioma, a brain cancer that is almost invariably fatal. Berg underwent standard treatment: an operation to remove the tumor, followed by chemotherapy and radiation to eradicate any cancer cells that might remain. [More]

Divining the Right Drug Imagine suffering from the crushing weight of major depression, then finally getting diagnosed and starting treatment with a drug--only to realize after two months that the medication, despite its unpleasant side effects, is not alleviating your depression. Unfortunately, this experience is far from rare: more than two thirds of patients with depression have no luck with the first medication they are prescribed and must also endure the withdrawal effects that come with discontinuing a drug before trying a new one. Finding the right treatment can prove a lengthy, painful process of trial and error. A new technology, however, may bypass this ordeal by gauging very early in a treatment regimen how well a drug is working based on the patient’s brain waves. The technology, called quantitative electro­enceph­alography (QEEG), measures a person’s brain-wave pattern with EEG and then compares it with a database of normal samples to detect abnormal function. In a study published in the September 2009 issue of the journal Psychiatry Research , scientists used QEEG to record brain activity in subjects with major depressive disorder before they began treatment, after one week on an antidepressant and after eight weeks on the drug--the period it takes such drugs to achieve full effect. Changes in the QEEG readout after just one week of medication predicted 74 percent of the time whether patients would experience either a recovery or a remission of symptoms by the end of eight weeks. [More]

TB or Not TB?: Novel Detector Could Shorten Testing Times, Aid Treatment Efforts Tuberculosis is a serious public health challenge in the developing world, where the infection claims roughly two million lives each year, according to the World Health Organization (WHO) . Yet the disease, which is a leading killer of patients with HIV/AIDS, is cumbersome to detect, resulting in delayed or inappropriate treatment, greater spread of the infection and preventable deaths. [More]

Few Studies Compare the Efficacy of Medical Treatments The forward momentum of medical progress is manifest, it could be argued, in the $50 billion spent in 2008 on pharmaceutical research and development in the quest to bring new drugs to market. But little scientific or governmental infrastructure exists to ensure that each new treatment is actually an improvement over existing therapies--and to tease out what therapies are best for which patients. [More]

Seeing the Little Picture: Novel Nanocoating Gives Atomic Force Microscope Users a Better Look at Individual Molecules Spotting a disease in its earliest stages can help to facilitate its treatment greatly, yet telltale clues are often hidden at a scale too small to study accurately. This hindrance has some researchers looking for ways to use high-powered atomic force microscopes (AFMs) to study individual molecules for disease markers [More]

Genetics in the Gut: Intestinal Microbes Could Drive Obesity and Other Health Issues Outnumbering our human cells by about 10 to one, the many minuscule microbes that live in and on our bodies are a big part of crucial everyday functions. The lion's share live in the intestinal tract, where they help fend off bad bacteria and aid in digesting our dinners. But as scientists use genetics to uncover what microbes are actually present and what they're doing in there, they are discovering that the bugs play an even larger role in human health than previously suspected--and perhaps at times exerting more influence than human genes themselves. [More]

Playing the Body Electric Each new generation of astronomers discovers that the universe is much bigger than their predecessors imagined. The same is also true of brain complexity. Every era’s most advanced technologies, when applied to the study of the brain, keep uncovering more layers of nested complexity, like a set of never ending Russian dolls. We now know that there are up to 1,000 different subtypes of nerve cells and supporting actors--the glia and astrocytes--within the nervous system. Each cell type is defined by its chemical constituents, neuronal morphology, synaptic architecture and input-output processing. Different cell types are wired up in specific ways. For example, a deep layer 5 pyramidal neuron might snake its gossamer-thin output wire, the axon, to a subcortical target area while also extending a connection to an inhibitory local neuron. Understanding how the brain’s corticothalamic complex creates any one conscious sensation necessitates delineating these underlying circuits for the 100 billion cells in the brain. [More]

Next-Gen Scientists Honored for Evolving Medicine and Renewables [Slide Show] The more mysteries that scientists unlock, the more opportunities emerge for the next generation of researchers to transform newfound knowledge into tomorrow's breakthroughs that serve society. The Lemelson–M.I.T. Program recognized several potential breakthroughs Wednesday in awarding four of its $30,000 Lemelson–M.I.T. Student Prizes to those from California Institute of Technology (Caltech), the Massachusetts Institute of Technology (M.I.T.), Rensselaer Polytechnic Institute (R.P.I.), and the University of Illinois at Urbana–Champaign (U.I.U.C.). [More]

Could Mini Labs and Plant-Based Vaccines Stop the Next Pandemic? The H1N1 virus's rapid spread worldwide last year exposed the weaknesses in the global system for swiftly developing, manufacturing and distributing vaccines for newly identified strains of influenza. In Texas, researchers are attacking the first two of these problems through Project GreenVax , which will use a plant-based approach to vaccine development and a modular manufacturing environment that can scale quickly as vaccine demand grows. [More]

RSS integration by RSSinclude