DMF

Editor's Note: The following is an excerpt from The Creative Destruction of Medicine: How the Digital Revolution Will Create Better Health Care (Basic Books, 2012), by Eric Topol, a professor of innovative medicine and the director of the Scripps Translational Science Institute.

When public health officials fret about the soaring incidence of diabetes in the U.S. and worldwide, they are generally referring to type 2 diabetes. About 90 percent of the nearly 350 million people around the world who have diabetes suffer from the type 2 form of the illness, which mostly starts causing problems in the 40s and 50s and is tied to the stress that extra pounds place on the body’s ability to regulate blood glucose. About 25 million people in the U.S. have type 2 diabetes, and another million have type 1 diabetes, which typically strikes in childhood and can be controlled only with daily doses of insulin.

An uncharted trawl through thousands of small molecules involved in the body's metabolism may have uncovered a potential route to treating pain caused by nerve damage.

Reprinted from Nature magazine

Seaweed may well be an ideal plant to turn into biofuel. It grows in much of the two thirds of the planet that is underwater, so it wouldn't crowd out food crops the way corn for ethanol does. Because it draws its own nutrients and water from the sea, it requires no fertilizer or irrigation. Most importantly for would-be biofuel-makers, it contains no lignin--a strong strand of complex sugars that stiffens plant stalks and poses a big obstacle to turning land-based plants such as switchgrass into biofuel .

Personal oral hygiene notwithstanding, your mouth is teeming with hundreds of species of microorganisms. Until now, researchers have had a tough time sorting out all these small species--and how they interact. A new multicolor fluorescent-labeling technology is allowing microbiologists to peer into the human mouth’s microscopic jungle and discover new dynamics among several key groups. The findings were presented last December at the American Society for Cell Biology’s annual meeting in Denver.

For years researchers have been trying to figure out the best ways of making plants produce biofuels. But there is a funda­mental problem: photosynthesis, the process by which plants convert sunlight into stored chemical energy, is highly inefficient. Plants turn only 1 to 3 percent of sunlight into carbohydrates. That is one reason why so much land has to be devoted to growing corn for ethanol, among other bad biofuel ideas. And yet plants also have many advantages: they absorb carbon dioxide at low concen­trations directly from the atmosphere, and each plant cell can repair itself when damaged.

Genetically engineered mosquitoes developed by British biotech firm Oxitec as an approach to controlling dengue fever have been caught up in controversy since 6,000 of them were deliberately released to an uninhabited forest in Malaysia in a trial in December 2010.